OTI region was created out of the then Volta region of Ghana by President, Nana Akuffo Addo.
This new region has the historical town of Dambai as its capital which It is located on the eastern side of the Oti River a tributary of the Volta Lake. The Oti Region is bordered by Republic of Togo to the east, the Northern region, to the south by the Volta Region, and to the west by the Volta Lake. It has 8 districts namely, Kadjiebi, Jasikan, Nkwanta North, Nkwanta South, Krachi East, Krachi Nchumuru, Biakoye District, Krachi West.
The vegetation consists predominantly of grassland, especially savanna with clusters of drought- resistant trees such as baobabs or acacias. Between December and April is the dry season. The wet season is between about July and November with an average annual rainfall of 750 to 1050 mm (30 to 40 inches). The highest temperatures are reached at the end of the dry season, the lowest in December and January. However, the hot Harmattan wind from the Sahara blows frequently between December and the beginning of February. The temperatures can vary between 14 °C (59 °F) at night and 40 °C (104 °F) during the day.